Current Opinion in Investigational Drugs is a monthly publication covering all therapeutic areas, in recognition of the increasingly multi-disciplinary nature of modern drug discovery and development. With Current Opinion in Investigational Drugs, we aim to help the reader by providing in a systematic manner:

• critical reviews of selected areas of investigational drug research
• expert evaluation of selected drugs currently in clinical trials
• selection of the most interesting papers and patents, annotated by experts.

Subject division
Six therapeutic categories are covered with each being featured in separate journal issues, and each therapeutic area being covered twice-yearly. The broad therapeutic categories and the specialist topics within each are as follows:

• Anti-infectives - Antifungals and antiparasitics; antibacterials (beta-lactams, glycopeptides and other agents); antibacterials (quinolones, macrolides and oxazolidinones); vaccines; antivirals (HIV); antivirals (non-HIV)
• Anti-inflammatory, Immunologicals and Biologicals -Musculoskeletal; respiratory; dermatology; nervous system; transplantation
• Cardiovascular and Renal - Hypertension and renal failure; stroke and angina; arrhythmia and heart failure; antithrombotics; hemostasis and hematological diseases; atherosclerosis, hypercholesterolemia and heart disease
• Endocrine and Metabolics - Diabetes; reproductive endocrinology; hormone disorders; bone metabolism and obesity
• Central and Peripheral Nervous System - Pain; neuro-urology and neurogastroenterology; neurodegenerative and cognitive disorders; affective/behavioral/personality disorders and substance abuse; neurology and neuroprotection; schizophrenia and psychosis
• Oncological - Cell signaling modulators; cytotoxic drugs; immunotherapeutic drugs and monoclonal antibodies; protein therapeutics, including growth factors; gene therapy; antisense inhibitors

Each issue contains the following sections:

Paper alerts - Expert commentary on a selection of recently published papers through all therapeutic areas is provided.
Patent alerts - Brief commentaries on the scientific and/or commercial significance of new patents covering all therapeutic areas selected and written by experts within their respective fields. These are presented beside the patent abstract from Thomson Scientific.
Patent selection - A selection of recently-issued patents of particular interest from the Current Patents Gazette is included. 
Editorial overviews - Short mini-reviews in which an area of interest to the pharmaceutical industry is critically reviewed in the context of recent developments. These pieces are intended to be personal, thought-provoking and controversial, where appropriate.
Reviews - Concise reviews presenting recent developments in a specific therapeutic area. Reviews are peer reviewed and focus predominantly on investigational drugs, or the therapeutic/commercial applications of new discoveries.
Drug evaluations - Expert commentary on the scientific and commercial potential of selected drugs in clinical trials are provided in each issue, in the form of drug evaluations. An evaluation is a review of the available literature (scientific and commercial) and acts as an expert guide to the bibliography, highlighting references of particular interest. Opinion on the drug's potential, with a personal viewpoint on its therapeutic and economic viability, are included. All drug evaluations are peer reviewed.