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Gazette Highlights News 2004

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Week 53:
  • Wednesday December 29th saw publication of 2,284 new PCT applications by WIPO, the output for “Week 53” of 2004. This brings the total for the year to 114,739, an average of 2165 per week...
  • The PDJ from the UKPTO is a little light in the SPC department this week, with no filings, grants or expiries reported...
  • An application from inventors named Holmes and Watson based at GSK’s Greenford site heightened the Christmas merriment in the Current Patents Gazette office this week. Entitled “Inhibitors of matrix metalloproteinase”,...
  • A0s from PDJ6032, Nov 24-30th - due for publication early June 2006...
Week 52:
  • This weeks PDJ announced that SPC/GB03/038 for enfuvirtide had been granted to Chiron on their EP181150 patent...
  • In a further SPC related development this week, the appeal by Yissum Research and Development Co against the Patent Office’s rejection of an SPC application (SPC/GB02/023) has been stayed following the High Court’s referral to the ECJ of two questions of interpretation of the SPC Regulation. The SPC had been rejected on grounds that marketing authorisations...
  • Also, following questions referred to the ECJ in another case, whether “combination of active ingredients of a medicinal product” for the purposes of Article 1(b) of the Regulation, meant that all components of the combination had to be active ingredients with a therapeutic effect...
Week 51:
  • The latest issue of sibprima, the IP newsletter from Società Italiana Brevetti, includes a useful commentary on EP148605, the Kirin-Amgen cases relating to erythropoietin (EPO) that was recently revoked by the UK House of Lords. This decision, taken on the grounds of lack of novelty...
  • In our “A0” section each week we take an early look at initial patent applications filed at the UK Patent Office. It takes five or six weeks for these bibliographic details to appear in the Patents and Designs Journal, so that at least a further 16 months must elapse before publication of the specification takes place, if indeed that stage is ever reached...
  • The grant of a UK SPC protecting AstraZeneca’s treatment for breast cancer, fulvestrant was formally announced in the PDJ this week. Based upon EP138504 this SPC gives protection to fulvestrant until 1st October 2009...
Week 50:
  • Very many of the chemical and pharmaceutical companies represented in this issue of our Gazette were also present as exhibitors at CPhI in Brussels earlier in the week. CPhI, for those who have not yet come across it, is a global industry forum now in its 15th year, the Convention on Pharmaceutical Ingredients. More than 1400 exhibitors...
  • Bayer Healthcare AG has filed on modified (anti)estrogens which originally we thought must be adducts of known compounds, since the title refers to targeted chemotherapy for tumors of hormone-dependent organs. However, after some research, we infer that a herbicide chemist...
  • This week’s PDJ contained a notice on the revocation of GB2235627 (which also has an SPC for a salmeterol xinafoate and fluticasone propionate combination). The order of events recorded in the Patent Status Information shows that the High Court ordered the patent revoked in April, but the revocation was stayed whilst GSK...
  • Also contained in the PDJ are details of the entry into force of the SPC for imiquimod, extending the protection for 3M’s Riker Laboratories to November 2009. Imiquimod, launched as Aldara in the US and Zartra in Europe, is an orally and topically active immune response modifier...
Week 49:
  • The UK Patents and Designs Journal (PDJ) this week includes notice of the grant of Supplementary Protection Certificate SPC/GB99/015 in relation to omeprazole sodium...
  • The UK Comptroller has allowed amendments to correct errors in the EP837672 specification granted to Yeda in November 2003. The case is likely to read on to the diabetes treatment DiaPep277...
  • The November Japanese patent gazette contained details of the grants of 8 patent extensions, with all but 2 of these being for agrochemicals. The two pharmaceutical references were both granted to Pfizer for azithromycin hydrate...
  • On Monday, November 29, 2004 the Court of Appeal for England and Wales ruled that Glaxo’s patent for its SEROXAT paroxetine hydrochloride anhydrate was valid but that Apotex did not infringe it. In Smithkline Beecham plc and others...
Week 48:
  • Two UK SPC applications have been published this week. The first assigned to Genentech relates to efalizumab the company's humanized anti-CD11a monoclonal antibody for the treatment of psoriasis...
  • Official confirmation that two SPCs have now entered into force was published in the PDJ this week. Both of these SPCs are assigned to Serono...
  • Pharmacia & Upjohn has this week published a PCT application disclosing a combination of irinotecan and revimid for the treatment of multiple myeloma...
  • Also published this week is the first PCT application from Chroma Therapeutics relating to the company's glyoxalase I inhibitor project...
  • Ranbaxy is set to challenge two of Pfizer's patents covering atorvastatin in the U.S. District Court...
  • UK initial ("A0") applications filed October 19th - 26th 2004...
Week 47:
  • Official notice of the expiry of a UK SPC protecting Tokyo Tanabe's beractant formulation was published this week. The SPC was based on GB2050832...
  • Also published this week were two UK SPC applications, both are assigned to Aventis and Imclone...
  • A process application from Ranbaxy this week is directed to the preparation of cell adhesion inhibitors originally described in WO0042053. Compounds covered in the earlier case...
  • is week also sees an interesting PCT application from Merck Sharp & Dohme. It discloses a combination of MSD's own aprepitant launched for the treatment of chemotherapy...
  • GlaxoSmithKline has recently filed several dedications on three of it patents relating to sumatriptan succinate (Imitrex)...
  • It is announced in last week's UK Patents and Designs Journal that EP668782 (Temple Univ & Thomas Jefferson Univ) has been revoked...
  • UK Initial ("A0") Applications filed October 12th - 19th 2004...
Week 46:
  • Lundbeck granted SPC protecting escitalopram...
  • Novo Nordisk files an SPC application for Levemir...
  • Official notice of the expiry of a UK SPC protecting the imaging agent ioversol was also published this week...
  • UK initial (“A0”) applications filed October 7th – October 13th 2004...
Week 45:
  • Patent Cooperation Treaty to enter into force in San Marino...
  • UK SPC relating to bivalirudin filed and angiomax SPC granted...
  • This week sees the publication of a flurry of patent applications from all over the world relating to the detection, prevention and/or treatment of Severe Acute Respiratory Syndrome (SARS) coronavirus infection...
  • We are used to seeing applications claiming new uses of existing compounds however, filings describing new actions are much rarer. This week sees the publication of such an application from Eisai...
  • Glaxo gives possible clues to glucocorticoids in inhaler application...
  • UK initial (“A0”) applications filed September 30th – October 6th 2004...
Week 44:
  • European Commission debate proposal for "Regulation of Medicinal Products for Paediatric Use"...
  • Patent extensions and applications for extensions from Japan...
  • Extensions from UK Patents and Designs Journal...
  • UK Initial ("A0") Applications filed September 22nd - 29th 2004...
Week 43:
  • SPC application filed for pregabalin...
  • Official confirmation that the UK SPC protecting Johnson & Johnson’s epilepsy drug topiramate entered into force was also published this week. This SPC entered in to force on 25th September following the expiry of EP138441...
  • A US application this week from IPCA claiming a formulation of paroxetine hydrochloride adds to the Indian company’s limited patenting profile, which boasts 3 PCT applications...
  • Amgen patent protecting EPO revoked by House of Lords...
  • A UK SPC application based on EP148605 was filed in 1993, however this was withdrawn in 1996. A French CCP protecting the product...
  • UK intial (“A0”) applications filed September 14th – September 21st...
Week 42:
  • This week sees the publication of a UK SPC application from Eli Lilly. The application attempts to extend protection for atomoxetine...
  • The formal announcement that an SPC protecting lomefloxacin has entered into force was published in the PDJ this week. Hokuriku Pharmaceutical Co...
  • Amendments which have been made to the specification of EP817864 under Section 27 of the UK Patents Act 1977 were advertised for opposition purposes on 13 October. The application to amend the specification...
  • Merck & Co are currently working on a research project of small molecule VEGFR-2 (Kdr) kinase inhibitors, for the treatment of cancer and other angiogenic disorders. In June of this year it was reported at the 29th National Symposium...
  • Novartis has filed six applications this week on combinations of their launched, ascomycin macrolactam derivative Elidel (pimecrolimus) with a wide range of compounds. Two previous combination cases indicate that Novartis...
  • UK intial (“A0”) applications filed September 7th – September 14th...
Week 41:
  • From this week’s UK Patents and Designs Journal (PDJ) we learn that Syria acceded to the WIPO Convention in August 2004. More importantly perhaps...
  • Also in the PDJ we are reminded of the grant of a Supplementary Protection Certificate (SPC) to Rovi for bemiparin, as reported last week. In addition, Wisconsin Alumni Research Foundation...
  • The September issue of the Japanese Patent Gazette gave details of extensions relating to three patents. Following the January 2004 launch in Japan as Prodif, Pfizer...
  • Berlex Labortaories, who as part of Schering are licensees for Cetus Corp’s (now Chiron) interferon beta-1b product, received a 5 year extension...
  • UK initial applications filed August 31st – September 1st 2004...
Week 40:
  • Bemiparin, the low molecular weight heparin (LMWH) product from Laboratorios Farmaceuticos Rovi SA, has been granted a UK Supplementary Protection Certificate (SPC), as reported in this week’s UK Patents and Designs Journal...
  • This week's PDJ also noted that the Yissum R&D Company of the Hebrew University of Jerusalem had lodged an appeal against the rejection...
  • The SPC had been rejected with the examiner citing earlier authorisations for calcitriol. Yissum proposed that the earlier authorisations...
  • Further SPC applications were published from Genzyme Corporation and Schering AG. Genzyme applied for an SPC on colesevelam hydrochloride...
  • The application from Schering covers the combination of estradiol and drospirenone, also called Yasmin in the Orange Book...
  • UK Initial (“A0”) Applications...
Week 39:
  • The UK Patent & Designs Journal (PDJ) published on the Autumnal Equinox includes a notice to the effect that the Patents Act 2004 came into force that same day. Although that sounds like an important event for those involved in patenting...
  • Also in the PDJ, entry into force of a Supplementary Protection Certificate (SPC) for troglitazone on August 30th 2004 is noted. This has the effect of extending...
  • A UK SPC application from Novartis was also published. The application covering mycophenolate monosodium salt is based upon EP892640...
  • UK initial applications filed August 18th – 23rd 2004...
Week 38:
  • The August Gazette from Japan contained details of a number of patent extension events. Two applications for 5 year extensions were reported for Eli Lilly’s Evista...
  • Pliva Pharmaceuticals had 3 applications which were granted five year extensions to their product patent for azithromycin and its use in treatment of a number of infections. Takeda gained...
  • AstraZeneca obtained almost 4 years extension for one of their goserelin patents whilst Sepracor...
  • Four applications, three to Otsuka Pharmaceuticals and one to Taiho Pharmaceuticals, were granted on TS-1 capsules...
  • Other Japanese companies that were granted extensions were Eisai and Santen Phramaceuticals with extensions of 3 and 4 years on 2 patents covering bunazosin hydrochloride...
  • UK Initial (“A0”) Applications...
Week 37:
  • UK SPC applications filed by Columbia Labs and Yamanouchi...
  • Xechem and University of Texas dispute ends...
  • This week ExonHit has disclosed labcodes for several compounds, the piperazine derivatives...
  • Roche revives uPAR antagonist programme...
  • UK Initial (“A0”) Applications...
Week 36:
  • In this week’s Patents & Designs Journal (PDJ) from the UK Patent Office, entry into force on August 10th 2004 is reported for the Novartis antiviral penciclovir...
  • Pfizer attracts attention this week with rather unusual claims to a method of treating hypertension. The focus is on Kiss-1 antagonists...
  • Ajinomoto provides technology relating to integrin alpha-4 inhibitors...
  • Chiesi discloses beta amyloid inhibitors...
  • UK Initial (“A0”) Applications...
Week 35:
  • Prejay patent used for five UK SPCs...
  • Novartis discloses new indications for the discontinued licarbazepine...
  • This week CareX has published three PCTs relating to LXR (Liver X Receptor) agonists. The company announced in March this year that an LXR modulator...
  • GSK received a ruling this week from the United States District Court in Wilmington, Delaware. The case involved use cases for GSK’s ondansetron...
  • UK Initial (“A0”) Applications...
Week 34:
  • The grant of Supplementary Protection Certificates (SPCs) for Shionogi’s rosuvastatin and Novartis’ lumiracoxib is formally reported...
  • This week, Altana Pharma AG filed for a UK SPC on ciclesonide, which gained UK approval in April 2004 for the treatment of asthma in adults...
  • GSK drops rosiglitazone countersuit...
  • This week AstraZeneca has two cases describing stable dispersions of solid, sub-micron particles in an aqueous medium. The medium contains an inhibitor that prevents particles growth...
  • Wisconsin gains European patent for QRX-101...
  • UK initial (“A0”) applications due to be published at the beginning of January 2005...
Week 33:
  • Two PCT applications published this week, from two different teams in California, seem to overlap...
  • Teva has this week continued its interest in the diabetes treatment nateglinide...
  • Vitrolife the Swedish company focusing on transplant and fertility systems, this week announced the patent approval...
  • Bristol Myers Squibb is facing opposition to its Atherosclerosis, Cerebrovascular ischemia and Myocardial...
  • Medimmune has filed two cases relating to Vitaxin. The PCTs describe a liquid formulation and a method of using the drug to treat various diseases...
  • GSK finds new use for NK1 antagonists...
  • UK Initial ("A0") Applications filed July 5th - 12th 2004...
Week 32:
  • Only two SPC events were reported in this weeks UK PDJ, the grant of Health Research Inc's SPC for recombinant canarypox viruses and vaccines...
  • Several patent extensions were reported in the Japanese Gazette for July, of which five were for Agrochemicals...
  • Sumitomo Pharmaceuticals gained around 3.5 years extension for one of their Japanese meropenem trihydrate...
  • Daiichi Suntory Pharma received extensions of more than 3 years to two patents for faropenem sodium, including the product patent...
  • Aventis patent application for enoxaparin rejected again...
  • This week saw the publication of research lead by Dr Friedrich Grimminger of the University of Geissen. This research involved...
  • Published this week is a case from Aventis disclosing the use of their launched recombinant human insulin analog Lantus...
  • Gilead has two cases published this week, one of which claims a combination of tenofovir disoproxil fumarate and emtricitabine...
  • UK Initial ("A0") Applications filed June 28th - July 5th 2004...
Week 31:
  • The expiry of the UK SPC covering Chiron's anticancer recombinant interleukin-2 compound aldesleukin...
  • Chinese companies have this week announced they intend to challenge the local patent for GSK's antidiabetic compound rosiglitazone...
  • Ortho appears to have a particular interest in the choline salt of topiramate...
  • GSK claim nasal pump sprays for glucorticoid agonist...
  • Application was made earlier this year to amend EP667852 (Pfizer Healthcare)...
  • Cortex Pharmaceuticals in collaboration with the University of California and Wake Forest University is seeking to gain protection on the use of AMPA...
  • Phase 2 Discovery appear to have added to their development pipeline...
  • 2-Deoxyglucose has been known as an anti-neoplastic agent for a number of years with articles stretching back as far as 1952. US company Threshold Pharmaceuticals...
  • UK Initial ("A0") Applications filed June 21st - 28th 2004...
Week 30:
  • This week a UK SPC application for Biogen's antibody treatment for Non-Hodgkin lymphoma...
  • Official notification of UK SPCs entering into force was also published this week...
  • The expiry of P&Us UK SPC covering ceftiofur was officially announced this week...
  • EP817864 claiming a diagnostic and therapeutic system for Crohn's disease and ulcerative colitis was granted in June 2002...
  • PCT applications from Aventis published this week and last characterize particular forms (A and C) of an antibacterial agent...
  • Arden Pharmaceuticals have this week published a PCT application disclosing diaryl methylpiperazine compounds...
  • Possible disclosure of EGS001 and FP1198...
  • UK Initial ("A0") Applications filed June 14th - 21st 2004...
Week 29:
  • Protein Design Labs have this week published a PCT application claiming the use of the discontinued investigational compound ALX-40-4C...
  • No new SPCs were lodged at the UK PTO this week. However, SPC GB03/017 was granted to Ortho-McNeil Pharmaceutical, Inc for the norelgestromin / ethinylestradiol...
  • Patent extensions from Japan...
Week 28:
  • Novartis attempt to protect eplerenone with an SPC...
  • A further UK SPC application was also published this week, this joint application from both Chiron and Novo Nordisk...
  • Another slightly unusual case saw Eli Lilly announcing the launch of Straterra (atomoxetine HCl) for treatment of ADHD...
  • UK Initial ("A0") Applications filed May 31st - June 7th 2004...
Week 27:
  • Supplementary Protection Certificate (SPC) events reported by the UK Patent Office this week include the grant of five years' additional protection for adefovir dipivoxil...
  • There seems to have been some confusion over the UK designation of EP200421 which covers Novo Nordisk's recombinant coagulation Factor V11a...
  • There has been some activity on the file of Lundbeck's EP1227088 prior to the expiry of the opposition period. On the grant of the European patent, covering the crystallization of R,S-citalopram...
  • The use of harkoseride, a peptide orginating with the University of Houston and currently in Phase II clinical trials, is claimed for treating allodynia...
  • UK Initial ("A0") Applications filed May 24th - 31st 2004...
Week 26:
  • Lead compounds from BMS, GSK, Pfizer and Roche...
  • Quebec-based ViroChem Pharma Inc makes its first foray into the arena of international patenting the publication of its first PCT applications claiming...
  • This week sees two interesting applications, both using specified food products to deliver therapy. One, filed in Japanese, comes from the Ghen Corporation and their method for treating...
  • UK Initial ("A0") Applications filed May 17th - 24th 2004...
Week 25:
  • Almirall Prodesfarma was granted a UK Supplementary Protection Certificate (SPC) on May 24th for its almotriptan migraine therapy...
  • Cabinet Alice de Pastors has just issued SPC News 17, and again we are very grateful to have this expert attorney's view of supplementary protection in the EU...
  • Shionogi is seeking protection for salts of one particular phospholipase A2 inhibitor, the basic molecule of which is already claimed in...
  • Workers at Ortho-McNeil's base in San Diego are working on histamine H3 antagonists with a structure similar to that of Gliatech's cipralisant...
  • Generic drug companies also feature this week in Section B, where claims to new uses and formulations of known active ingredients are covered...
  • UK Initial ("A0") Applications filed May 10th- 17th 2004...
Week 24:
  • SPCs from Millenium (bortezomib) and Euro-Celtique (Hydromorphone hydrochloride)...
  • Australian Patent Office denies Pfizer...
  • Islamic Republic of Pakistan enters Paris Convention...
  • Japan Tobacco and Tularik claim diacylglcerol acyltransferase (DGAT) inhibitors...
  • First applications from ProSkelia SAS and Shenzhen Chipscreen Biosciences...
  • Peptech and Agenix merger off...
  • UK Initial ("A0") Applications filed May 3rd - 10th 2004...
Week 23:
  • Teva and Ciba Speciality Chemical join forces over atorvastatin...
  • This week sees the publication of two Ranbaxy patent applications disclosing combined formulations of biguanide, formulated in a extended release form...
  • SPC for Sumitomo's meropenem enters into force...
  • UK Initial "A0" Applications filed April 26th - May 3rd 2004...
Week 22:
  • PIUG Conference, Baltimore...
  • Mercury Therapeutics, a Massachusetts based biopharmaceutical company targeting dysfunctional signal transduction...
  • Wyeth has a PCT that describes using a combination of gemtuzumab ozogamicin and an anthracycline of purine nucleoside analog to treat acute leukemia...
  • Large-scale production of therapeutic antibodies from Abbott Bioresearch...
Week 21:
  • RIP EU Community Patent?...
  • The EPO has granted EP637237 to NPS and Brigham & Women's Hospital this week. The subject matter is calcimimetic...
  • Cyclacel has published four PCTs disclosing the use of CYC-202 (roscovitine) in combination with mitoxantrone, cisplatin, docetaxel and gemcitabine...
  • This week sees a PCT publication from Egalet covering a controlled release formulation of carvedilol...
  • Fujisawa has a PCT published disclosing a combination of tacrolimus or its derivatives with...
  • XenoPort, Inc of Santa Clara, California has an application published this week claiming prodrugs of Lilly's launched antitumor agent gemcitabine...
  • Wellspring Pharmaceuticals has a published US application this week relating to water-soluble formulations of Sn-mesoporphyrin...
Week 20:
  • Expiry of Merck & Co's UK SPC for lisinopril and hydrochlorothiazide...
  • The UK SPC covering Glaxo's asthma treatment salmeterol entered into force on 18th April following the expiry of GB2140800...
  • A decision was issued on 14th May by the Australian Patent Office regarding the opposition by Lek against SB's Australian patent covering a pediatric formulation of amoxycillin/clavulanic acid...
  • An application has been made in the UK under Section 28 of the Patents Act 1977 to restore EP626858 entitled "Use of protease inhibitors as antiviral agents"...
  • Bionumerik has a a non-polyglutamylatable dihydrofolate reductase inhibitor MDAM currently in Phase I for cancer treatment...
  • An application from the University of California this week continues the work of Heike Wulff and her team in the systhesis and use of triarylmethane (TRAM)...
  • Pfizer and Poly-Med Inc have collaborated on two PCTs published this week. They disclose liquid phase conjugates of ziprasidone...
Week 19:
  • SPCs for quinapril hydrochloride and vinorelbine expire...
  • Glaxo's failure to market zanamivir sufficiently is the subject of litigation filed by Australian biotech company, Biota. The nasally administered viral replication inhibitor...
  • First IP filing for Chong Kun Dang's anticancer telomerase inhibitors...
  • Telmisartan prodict patent specification amended...
  • Zentiva Hlohovec has first application published...
  • Three applications have been filed this week from Pizer relating their atypical antipsychotic ziprasidone, used for the treatment of schizophrenia...
  • More university filings in relation to imatinib...
  • UK Initial "A0" Applications filed March 30th - April 6th 2004...
Week 18:
  • Breaking news as we went to press last week was the potentially very important merger between Aventis and Sanofi-Synthelabo...
  • SPC filed for AstraZeneca's fulvestrant. Genetech's trastuzumab and Emory's emtricitabine...
  • The content of an AstraZeneca PCT application this week points towards the identity of its lead atrial repolarization delaying agent, AZD-7009...
  • Oxford Glycosciences and Bayer's Japanese research company working together on anti-asthma compounds...
  • UK Initial "A0" Applications filed March 23rd - 30th 2004...
Week 17:
  • SPC application from Orion for Stalevo combination...
  • Bayer increases activity surrounding nitrile analog of moxifloxacin...
  • In the last few years, Bristol Myers Squibb has been investigating a series of inosine monophosphate dehydrogenase (IMPDH) inhibitors, based on VX-497...
  • AstraZeneca's legal whirlwind surrounding budesonide/formoterol combination...
  • E Merck has two applications published this week relating to antibodies that bind to ErbB1 receptors present on cancer tissues. The first relates to a combination of the antibodies EMD-55900...
  • Novartis, who has recently filed a number new use and combination cases for the anti-cancer drug Imatinib...
  • The biotechnology company Kosan Biosciences filed two applications that were published this week relating to the microtubule inhibitor epothilone D...
  • AstraZeneca have three combination cases published this week, two involving their Phase II anti-cancer compounds, ZD6474 and ZD6126...
  • UK Initial "A0" Applications filed March 9th - 22nd 2004...
Week 16:
  • Thomson Corporation acquires Newport Strategies...
  • Generic drug companies and API manufacturers with applications published this week include firms from India, Italy, Spain, Korea and Poland...
  • Potentially more contentious is the application from Dr Reddy's Laboratories, in which a crystalline form of amlodipine maleate is claimed in terms of its X-ray diffraction parameters...
  • The Spanish company Ragactives targets the antihistamine mizolastine, while a tibolone process is claimed by Polish company Anpharm...
  • The disclosure that Dr Reddy's has opened a Drug Master File for quetiapine, the active ingredient of AstraZeneca's anti-schizophrenic Seroquel...
Week 15:
  • Yamanouchi consolidates platelet synthesis stimulant protection...
  • UK Initial "A0" Applications filed March 3rd - 9th 2004...
Week 14:
  • SPCs: Moxifloxacin granted, gemcitabine in force and amlodipine expires...
  • Two UK SPC applications were also published this week. The first is from Yeda R&D and covers...
  • Two cases relating to imatinib have appeared this week, each assigned to an American university. Imatinib was developed by Novartis...
  • The resource being put by Merck & Co into PDE 4 inhibitors may, on the evidence of patent filing, have yielded a lead compound. Of the 76 specific compounds...
  • Contrary to a disclosure in Bioorganic & Medicinal Chemistry Letters in 2001, GlaxoSmithKline's interest in PPAR...
  • UK Initial "A0" Applications filed February 23rd - 30th 2004...
Week 13:
  • SPC in force for esomeprasole and applications for estradiol/trimegestone, isopropyl unoprostone...
  • An application this week from the Medical University of South Carolina (MUSC) on methods and kits for testing drug susceptibility of HIV features one American inventor...
  • Aventis win appeal against refusal of EP grant...
  • Talampanel applications granted for Lilly...
  • UK Initial "A0" Applications filed February 16th - 23rd 2004...
Week 12:
  • Extended protection for Mononine...
  • Kissei protects lead dysuria drug...
  • Enzyme-catalyzed chemistry from Rome...
  • More anticholinergenic claims from Boehringer...
  • UK Initial "A0" Applications filed February 10th - 16th 2004 2004...
Week 11:
  • International Patent Information Conference and Exposition 2004...
  • Extended protection for monoclonal antibody...
  • Pfizer turns green...
  • UK Initial "A0" Applications filed February 3rd - 10th 2004...
Week 10:
  • Japanese patent extensions...
  • Pfizer has a European patent granted this week. The subject matter is a process to CP-118954, an acetyl cholinesterase (ACE) inhibitor...
  • This week sees the publication of two patent applications from the University of Connecticut relating to novel biphenyl, biphenyl-like and tricyclic cannabinoids...
  • UK Initial "A0" Applications filed January 27th - February 3rd 2003...
Week 09:
  • This week sees the expiry of Eli Lilly's UK SPC covering its Parkinson's treatment pergolide...
  • The UK SPC covering cefprozil, a Bristol-Myers Squibb antibiotic, came into force on 27th January after the expiry of GB2135305...
  • A team at Eisai's London-based laboratories within University College is researching Jun N terminal kinase inhibitors...
  • A more mysterious final product is that of which the Chengdu List Pharmaceutical Company has made salts...
  • A number of new processes to marketed drugs or their intermediates/physical forms are covered by companies in India (Natco - citalopram, tamsulosin), Korea...
  • Generx has two applications relating to micellar formulations of large-molecule drugs for administration through the buccal region of the mouth...
  • Vaccine Research International PLC has filed a UK initial application (A0) for a safe vaccine to prevent bacterial infections. The company is developing a vaccine...
  • UK Initial "A0" Applications filed January 20th - 27th 2003...
Week 08:
  • Bristol Myers Squibb's UK SPC for cefprozil entered into force on 27th January...
  • Warner-Lambert attracts attention this week with a block of 22 closely linked PCT applications relating to novel inhibitors of the collagenase...
  • Ranbaxy, at one time seen as primarily a generic drug manufacturer, now has claims to novel M3 muscarinic receptor antagonists...
  • This week sees another of WIPO's occasional specification mix-ups with the inside pages of WO2004014361 (Glaxo, claiming antibacterial aminocyclohexene quinolines) and...
  • A new biotech start-up company, AngioDesign Inc, is likely to license what appears to be its core screening technology disclosed...
  • It would appear from this week's patent evidence, that Pfizer has identified CP-481715 as the lead compound in its development program for CCR1 antagonists...
  • Boehringer Ingelheim is continuing to disclose uses and formulations of its p38 MAP kinase inhibitor doramapimod...
  • UK Initial "A0" Applications filed January 13th - 20th 2003...
Week 07:
  • The announcement of the grant of a UK SPC to Novartis covering its atopic dermatitis treatment, pimecrolimus...
  • An SPC granted to Pharmacia & Upjohn, also receiving a five year protection period, came into force this week following the expiry of EP121036...
  • Cancer Research UK and Duke University have been granted a Europe-wide patent on BRCA2 gene sequences...
  • Generic companies are not especially prominent in this week's new publications, though Teva is an exception, with PCT applications relating to gatifloxacin, clopidogrel and aztreonam...
  • This week saw the publication of Wackvom Ltd's sixth PCT. All of the company's applications relate to therapies...
  • UK Initial "A0" Applications filed January 6th - 13th 2003...
Week 06:
  • This week sees the formal announcement of the UK SPC expiries for ramipril and reboxetine...
  • Pfizer compounds appear to be the key targets of generics companies this week, with applications from Chemagis...
  • Other generic activity this week is limited to two applications from Teva...
  • This week, Sepracor has disclosed the use of a series of known cyclooxygenase 2 (COX 2) inhibitors...
  • Lundbeck announced on February 6th 2004, that it has settled patent infringement cases against Ratiopharm and Destin Pharma...
  • This week saw the publication of the first PCT to arise from Hawaii Biotech's ROS (reactive oxygen species) program...
  • Albachem Ltd, a small, privately owned custom peptide synthesis company based in Scotland, has filed its first patent applications with the help of pharmaceutical giant Amersham Biosciences...
  • UK Initial "A0" Applications filed December 19th - 24th 2003...
Week 05:
  • Three Supplementary Protection Certificate (SPC) expiries were the only SPC events reported in the UK Patents and Designs Journal...
  • Indian and Israeli manufacturers are among the companies claiming process enhancements in this week's publications, but China, Japan, Korea, Italy and Croatia...
  • Tanabe Seiyaku Co Ltd seems to have no obvious reason for filing initial applications in the UK, but on December 20th 2003 did so as a means of initiating protection for novel compounds...
  • Ultrasis plc, now claiming apparatus and systems for treating epilepsy, specializes in computerized, drug-free solutions...
  • Temrel Inc is a rarity, in the sense that it has filed a couple of UK initial patent applications, but nothing else is known of the enterprise, beyond...
  • UK Initial "A0" Applications filed December 19th - 24th 2003...
Week 04:
  • For the second consecutive week the UK Patent Office has no Supplementary Protection Certificate (SPC) news to report. However, from Japan...
  • This week sees the announcement of a UK SPC application covering Abbott's paricalcitol. This application is based on Wisconsin Alumni Research Foundation's...
  • AstraZeneca has a very tight cluster of four PCT applications published this week, all filed on the same mid-July day in 2002, and all naming a UK/US/Swedish inventor team...
  • Indian contributors to the generic drugs scene published this week include process development cases from Zydus-Cadila (pioglitazone), Cipla (paclitaxel) and Alembic...
  • In 2002 Unichem Laboratories Ltd, an Indian research company, set up a joint venture in the UK with the erstwhile directors of Bioglan Generics...
  • UK Initial "A0" Applications filed December 16th - 23rd 2003...
Week 03:
  • No Supplementary Protection Certificate (SPC) happenings are reported in this week's Patents & Designs Journal...
  • CLS Laboratories Inc of Daejeon-city in Korea, has virtually no international patent property to date, and very little is know of the company...
  • The drug delivery technology covered in Section E (devices) includes implants from Debiopharm, Polyzenix, and (apparently) Scimed Life Systems; electroporation from Inovio...
  • Metered dose inhalation preparations and their dispensers feature in initial UK patent applications from two different companies this week. 3M Innovative Properties Co...
  • UK Initial "A0" Applications filed December 8th - 15th 2003...
Week 02:
  • The UK Patent Office's Patents & Designs Journal (PDJ) for January 7th 2004 includes notices of grant for two Supplementary Protection Certificates...
  • Nigerian companies are represented in the Gazette only infrequently, but this week there is a chemical process case from Urah Resources of Ayangba...
  • From the generic drug sector there are two process cases from Biocon India Ltd, both using solid-state batch-fed fermentation...
  • We came across an invention which could have a profound effect on the future of the drug industry...
  • UK Initial "A0" Applications filed December 1st - 8th 2003...
Week 01:
  • Ropinirole's "double SPC"...
  • BrainsGate's new approach to CNS...
  • Missing drug patent?...
  • Nevirapine and its sequel...
  • Generics overview...
  • UK Initial "A0" Applications filed November 17th - 24th 2003...
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